The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 21, 2020

Filed:

Dec. 12, 2014
Applicant:

Cornell University, Ithaca, NY (US);

Inventors:

Rajiv R. Ratan, Scarsdale, NY (US);

Saravanan S. Karuppagounder, White Plains, NY (US);

Assignee:

CORNELL UNIVERSITY, Ithaca, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/47 (2006.01); A61K 31/4709 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4709 (2013.01); A61K 31/47 (2013.01);
Abstract

Methods for treating a patient suffering from neural cell injury, the method comprising administering to the patient an effective amount of a HIF prolyl-4-hydroxylase inhibiting compound having the following general formula (1) wherein Ris a cyclic group containing at least three and up to seven carbon atoms and optionally containing one or more heteroatoms selected from O, N, and S, and optionally attached to the shown carbon atom by a linking group; Ris independently selected from said cyclic groups of Rand acyclic hydrocarbon groups Rcontaining up to twenty carbon atoms; Ris selected from hydrogen atom and hydrocarbon groups containing up to six carbon atoms; Rand Rare independently selected from hydrogen atom, hydrocarbon groups containing up to three carbon atoms, halogen atom, and polar groups, as well as methylene-linked versions thereof; and t is 0 or 1.


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