The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Oct. 21, 2016
Applicant:
Novartis Ag, Basel, CH;
Inventors:
Brian Little, Carlsbad, CA (US);
Jennifer Bordeaux, Carlsbad, CA (US);
Assignee:
Novartis AG, Basel, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/483 (2006.01); G01N 21/64 (2006.01); G01N 33/574 (2006.01); G01N 33/48 (2006.01); G16H 50/30 (2018.01); G16H 40/63 (2018.01); G16H 30/20 (2018.01); G06T 7/00 (2017.01);
U.S. Cl.
CPC ...
G01N 33/4833 (2013.01); G01N 21/6456 (2013.01); G01N 33/48 (2013.01); G01N 33/57492 (2013.01); G06T 7/0012 (2013.01); G16H 30/20 (2018.01); G16H 40/63 (2018.01); G16H 50/30 (2018.01); G01N 21/6428 (2013.01); G01N 2021/6439 (2013.01); G01N 2800/52 (2013.01); G06T 2207/30096 (2013.01);
Abstract
The invention relates, in part, to systems and methods for scoring a sample containing tumor tissue from a cancer patient. The score is representative of a nearness between at least one pair of cells, a first member of the least one pair of cells expressing a first biomarker and a second member of the at least one pair of cells expressing a second biomarker that is different from the first biomarker. The score obtained from these methods can be indicative of a likelihood that a patient may respond positively to immunotherapy.