The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Sep. 20, 2019
Atyr Pharma Inc., San Diego, CA (US);
Chi-Fang Wu, San Diego, CA (US);
Darin Lee, San Diego, CA (US);
Jeffry D. Watkins, Encinitas, CA (US);
Kristi Piehl, San Diego, CA (US);
Kyle P. Chiang, Cardiff, CA (US);
Marc Thomas, Vista, CA (US);
Minh-Ha Do, San Diego, CA (US);
Ying Buechler, Carlsbad, CA (US);
John D. Mendlein, Encinitas, CA (US);
aTyr Pharma, Inc., San Diego, CA (US);
Abstract
The present invention provides histidyl-tRNA synthetase and Fc region conjugate polypeptides (HRS-Fc conjugates), such as HRS-Fc fusion polypeptides, compositions comprising the same, and methods of using such conjugates and compositions for treating or diagnosing a variety of conditions. The HRS-Fc conjugates of the invention have improved controlled release properties, stability, half-life, and other pharmacokinetic and biological properties relative to corresponding, unmodified HRS polypeptides.