The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2020

Filed:

Jun. 17, 2009
Applicants:

Karl Deisseroth, Palo Alto, CA (US);

Albrecht Stroh, Munich, DE;

M. Bret Schneider, Portola Valley, CA (US);

Raag D. Airan, Menlo Park, CA (US);

Inventors:

Karl Deisseroth, Palo Alto, CA (US);

Albrecht Stroh, Munich, DE;

M. Bret Schneider, Portola Valley, CA (US);

Raag D. Airan, Menlo Park, CA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 13/00 (2006.01); C12N 5/0735 (2010.01); C12N 5/0793 (2010.01); A61N 5/06 (2006.01); C12M 1/00 (2006.01); C12N 15/86 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0606 (2013.01); A61N 5/0601 (2013.01); C12M 21/02 (2013.01); C12N 5/0619 (2013.01); C12N 15/86 (2013.01); C12N 2500/38 (2013.01); C12N 2501/115 (2013.01); C12N 2501/119 (2013.01); C12N 2501/385 (2013.01); C12N 2501/41 (2013.01); C12N 2501/998 (2013.01); C12N 2506/02 (2013.01); C12N 2510/00 (2013.01); C12N 2529/10 (2013.01); C12N 2535/00 (2013.01); C12N 2740/00043 (2013.01);
Abstract

According to one aspect and example, a method for facilitating cellular interactions in biological tissue provides controllable activation of a selected type of stem cell among a plurality of cell types present in the tissue. The method includes various steps including the introduction of a microbial opsin into a region of the tissue that includes a selected type of stem cell, by expressing the microbial opsin in the stem cell. A light source is then introduced near the stem cell, and the light source is used to controllably activate the light source to direct pulses of illumination from the light source to the selected type of stem cell, for selectively controlling the growth and development of the stem cell in a manner that is independent of the growth and development of the other types of cells.


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