The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2020

Filed:

Aug. 22, 2017
Applicant:

Idex Health and Science Llc, Oak Harbor, WA (US);

Inventors:

Victor Simonyi, Healdsburg, CA (US);

Darrin Kurt Pickle, Santa Rosa, CA (US);

James Smyth, Santa Rosa, CA (US);

Craig Love, Santa Rosa, CA (US);

Assignee:

IDEX Health & Science LLC, Rohnert Park, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12M 1/34 (2006.01); C12M 1/00 (2006.01); C12Q 1/02 (2006.01); C12M 3/00 (2006.01);
U.S. Cl.
CPC ...
C12M 41/00 (2013.01); C12M 23/28 (2013.01); C12M 23/40 (2013.01); C12M 23/44 (2013.01); C12M 23/52 (2013.01); C12M 29/04 (2013.01); C12M 41/30 (2013.01); C12Q 1/02 (2013.01);
Abstract

Apparatus and methods for providing a single-use, disposable module or manifold for testing and analysis of bioprocesses. A module comprising a valve, a filter or guard column, an affinity column, and a flow cell is provided with several ports for receiving tubing connections for a sample and one or more solvents, as well as one or more outlet ports for connections to one or more waste reservoirs. The flow cell may use UV light to determine a protein concentration of a sample in one particular example. The module can be connected directly or indirectly to a bioreactor containing the bioprocess and material to be sampled, and can be disposed of once a production run has been completed. In addition, manifolds are provided which can be embodied as a valve assembly, and which can comprise the same components and features as the disposable module. The manifolds and modules are compact and easy to use. A portable device for use with a module is also provided.


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