The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Jun. 21, 2016
Applicant:
Korea Institute of Industrial Technology, Cheonan-si, Chungcheongnam-do, KR;
Inventors:
Woo-Jong Lee, Seongnam-si, KR;
Sung-Gun Kim, Chungcheongbuk-do, KR;
Dong-Mok Lee, Daegu, KR;
Hee-Kyung An, Daegu, KR;
Chi-Min Choi, Seongnam-si, KR;
Assignee:
Korea Institute of Industrial Technology, Cheonan-si, Chungcheongnam-do, KR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/47 (2006.01); C07K 14/705 (2006.01); C07K 19/00 (2006.01); C12N 15/63 (2006.01); G01N 33/53 (2006.01); G01N 33/538 (2006.01); C12N 15/62 (2006.01);
U.S. Cl.
CPC ...
C07K 14/705 (2013.01); C07K 14/47 (2013.01); C07K 19/00 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); G01N 33/53 (2013.01); G01N 33/538 (2013.01); C07K 2319/00 (2013.01); C07K 2319/20 (2013.01); C07K 2319/21 (2013.01); C07K 2319/50 (2013.01); C07K 2319/75 (2013.01); C07K 2319/95 (2013.01);
Abstract
The present disclosure relates to a method for producing a TLR5 agonist protein. According to the present disclosure, the TLR5 agonist protein can be easily separated and purified after biotechnological production. In particular, the fusion partner used for separation and purification is effectively removed so as to minimize the possibility of inhibiting binding to TLR5 and inducing an immune response by the fusion partner.