The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Jul. 31, 2019
Applicant:
Farmabios S.p.a., Gropello Cairoli, IT;
Inventors:
Enrico Torregrossa, Trapani, IT;
Marco Brusasca, Valenza, IT;
Cristina Manfrotto, Gropello Cairoli, IT;
Assignee:
FARMABIOS S.P.S., Gropello Cairoli (PV), IT;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C08J 7/00 (2006.01); C07J 7/00 (2006.01);
U.S. Cl.
CPC ...
C07J 7/002 (2013.01); C07B 2200/13 (2013.01);
Abstract
A method for the purification of allopregnanolone is disclosed. Allopregnanolone prepared from isopregnanolone contains impurities such as triphenylphosphine oxide and other unknown impurities. To remove these impurities and purify allopregnanolone, the allopregananolone is dissolved in acetonitrile, and crystallized from the acetonitrile. The resulting crystallized allopregnanolone may then be re-crystallized from acetonitrile to further purify the allopregnanolone.