The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Aug. 14, 2019
Applicants:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Torrey Pines Institute for Molecular Studies, Port st. Lucie, FL (US);
Inventors:
Said M. Sebti, Tampa, FL (US);
Yangmei Li, Port St. Lucie, FL (US);
Richard A. Houghten, Port St. Lucie, FL (US);
Assignees:
H. Lee Moffitt Cancer Center and Research Institute, Inc., Tampa, FL (US);
Torrey Pines Institute for Molecular Studies, Port St. Lucie, FL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/429 (2006.01); A61K 35/00 (2006.01); C07D 513/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 513/04 (2013.01); A61K 31/429 (2013.01); A61P 35/00 (2018.01); C07C 2601/14 (2017.05); C07C 2601/16 (2017.05); C07C 2602/10 (2017.05);
Abstract
Compositions and methods for inhibits the binding of GTP to oncogenic mutant KRas are disclosed. These compositions may be used in method to treat a subject with cancer. In particular, the compositions may be used to treat cancers involving overactive Ras signaling.