The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Oct. 24, 2017
Hangzhou Hertz Pharmaceutical Co., Ltd., Hangzhou, Zhejiang Province, CN;
HANGZHOU HERTZ PHARMACEUTICAL CO., LTD., Hangzhou, CN;
Abstract
The present invention relates to a selective Bruton's tyrosine kinase (BTK) inhibitor compound, a pharmaceutical composition, preparation and use thereof in preparation of a drug. The compound of the present invention has a structure of Formula II or Formula II': Re is selected from H, CH, C2-C6 alkyl, C1-C6 azaalkyl, and C1-C6 oxaalkyl, wherein CH, C2-C6 alkyl, C1-C6 azaalkyl and C1-C6 oxaalkyl are further substituted with amino, hydroxyl, and C1-C3 alkyl;Y, Y, Yand Yare independently selected from C(Rf) and N, and at least one of Y, Y, Yand Yis N, wherein Rf is selected from H, halogen, C1-C3 alkyl, —CF, and —CFH.