The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Sep. 01, 2017
Applicant:
Vanderbilt University, Nashville, TN (US);
Inventors:
P. Jeffrey Conn, Brentwood, TN (US);
Craig W. Lindsley, Brentwood, TN (US);
Corey R. Hopkins, Bennington, NE (US);
Andrew Felts, Brentwood, TN (US);
Aaron M. Bender, Nashville, TN (US);
Assignee:
Vanderbilt University, Nashville, TN (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); A61K 31/496 (2006.01); A61K 31/541 (2006.01); A61K 31/4545 (2006.01); A61K 31/4725 (2006.01); A61K 31/553 (2006.01); A61K 31/47 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01); A61K 31/4545 (2013.01); A61K 31/47 (2013.01); A61K 31/4725 (2013.01); A61K 31/496 (2013.01); A61K 31/5377 (2013.01); A61K 31/541 (2013.01); A61K 31/553 (2013.01); A61K 45/06 (2013.01);
Abstract
Compounds which are useful as allosteric potentiators/positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4) of the following formula: synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurological and psychiatric disorders or other disease state associated with glutamate dysfunction.