The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2020

Filed:

Jun. 27, 2017
Applicant:

Hangzhou Rex Pharmaceutical Co., Ltd., Hangzhou, Zhejiang, CN;

Inventors:

Yonghui Wang, Zhejiang, CN;

Juan Zhou, Zhejiang, CN;

Yujun Gao, Zhejiang, CN;

Dong Wang, Zhejiang, CN;

Binbin Hong, Zhejiang, CN;

Ximing Shen, Zhejiang, CN;

Yaodong Wu, Zhejiang, CN;

Chunqi Li, Zhejiang, CN;

Assignee:

HANGZHOU REX PHARMACEUTICAL CO., LTD., Hangzhou, Zhejiang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61P 35/00 (2006.01); A61K 31/506 (2006.01); C07D 491/22 (2006.01); C07D 405/14 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/506 (2013.01); A61P 35/00 (2018.01); C07D 405/14 (2013.01); C07D 491/22 (2013.01);
Abstract

The present invention discloses a compound for regulating protein kinase activity and used for treating or preventing diseases associated with protein kinases. Specifically, the present invention relates to a benzofuran pyrazole amine protein kinase inhibitor which belongs to compounds that regulate anaplastic lymphoma kinase (ALK), and provides a method of preparing such a compound and a pharmaceutical use of such a compound in the treatment or prevention of diseases associated with ALK. The inhibitor can solve the problem of the drug resistance of the first generation and the second generation of ALK inhibitors.


Find Patent Forward Citations

Loading…