The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Mar. 31, 2016
Applicants:
Dana-farber Cancer Institute, Inc., Boston, MA (US);
Fondazione Centro San Raffaele, Milan, IT;
Inventors:
Nathanael S. Gray, Boston, MA (US);
Sara Buhrlage, Somerville, MA (US);
Kenneth Anderson, Wellesley, MA (US);
Francesca Cottini, Columbus, OH (US);
Giovanni Tonon, Milan, IT;
Assignees:
DANA-FARBER CANCER INSTITUTE, INC., Boston, MA (US);
FONDAZIONE CENTRO SAN RAFFAELE, Milan, IT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 401/14 (2006.01); C07D 401/04 (2006.01); C07D 405/14 (2006.01); C07D 413/14 (2006.01); C07D 213/73 (2006.01); C07D 409/14 (2006.01); C07D 413/04 (2006.01); C07D 417/14 (2006.01); C07D 513/04 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
C07D 401/14 (2013.01); A61P 35/00 (2018.01); C07D 213/73 (2013.01); C07D 401/04 (2013.01); C07D 405/14 (2013.01); C07D 409/14 (2013.01); C07D 413/04 (2013.01); C07D 413/14 (2013.01); C07D 417/14 (2013.01); C07D 513/04 (2013.01);
Abstract
The application relates to compounds of Formula (I'): which modulate the activity of a kinase (e.g., STK4), a pharmaceutical composition comprising the compound, and a method of treating or preventing a disease or disorder associated with the modulation of a kinase, such as STK4.