The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2020

Filed:

Oct. 28, 2016
Applicant:

Aska Pharmaceutical Co., Ltd., Tokyo, JP;

Inventors:

Makoto Okada, Kanagawa, JP;

Youichi Nakano, Kanagawa, JP;

Takashi Nose, Kanagawa, JP;

Takahiro Nishimoto, Kanagawa, JP;

Satoshi Maeda, Kanagawa, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 239/36 (2006.01); C07D 401/04 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); C07D 403/04 (2006.01); C07D 405/14 (2006.01); C07D 409/04 (2006.01); C07D 417/04 (2006.01); A61K 31/506 (2006.01);
U.S. Cl.
CPC ...
C07D 239/36 (2013.01); C07D 401/04 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C07D 403/04 (2013.01); C07D 405/14 (2013.01); C07D 409/04 (2013.01); C07D 417/04 (2013.01);
Abstract

A compound represented by the formula (1), or a salt thereof (X represents carbonyl group, or sulfonyl group; Rrepresents hydrogen atom, a halogen atom, an alkyl group, an alkanoyl group, cyano group, or carboxyl group; Rrepresents an alkyl group, a cyclic carbon group, or a heterocyclic group; Rrepresents hydrogen atom, or 1 to 3 substituents; Rand Rrepresents hydrogen atom, a halogen atom, or an alkyl group; and Rrepresents an alkyl group, or an alkoxy group), which has an mPGES-1 inhibitory action, and is useful as an active ingredient of a medicament for prophylactic and/or therapeutic treatment of inflammation, pain, rheumatism, and the like.


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