The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Aug. 16, 2017
Applicant:
City University of Hong Kong, Kowloon, HK;
Inventors:
Assignee:
CITY UNIVERSITY OF HONG KONG, Kowloon, HK;
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); A61K 48/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C12N 15/90 (2006.01); C12N 9/22 (2006.01); A61K 35/13 (2015.01); A61K 35/14 (2015.01); G01N 33/49 (2006.01); C12N 15/88 (2006.01); C12N 5/078 (2010.01); A61K 35/12 (2015.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 48/0075 (2013.01); A61K 35/13 (2013.01); A61K 35/14 (2013.01); A61K 48/005 (2013.01); A61K 48/0008 (2013.01); A61K 48/0041 (2013.01); A61K 48/0091 (2013.01); C12N 5/0641 (2013.01); C12N 9/22 (2013.01); C12N 15/88 (2013.01); C12N 15/907 (2013.01); G01N 33/491 (2013.01); A61K 35/00 (2013.01); A61K 2035/128 (2013.01); C12N 2310/11 (2013.01); C12N 2310/122 (2013.01); C12N 2310/20 (2017.05);
Abstract
A method of RNA delivery using extracellular vesicles (EVs) derived from red blood cells (RBCs). The method comprises the purification and electroporation of the EVs and applying the RNA-loaded EVs to target cells. The method further comprises the treatment of cancer using the RNA-loaded EVs.