The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2020

Filed:

Nov. 02, 2018
Applicants:

Industry-university Cooperation Foundation Hanyang University, Seoul, KR;

Industry-university Cooperation Foundation Hanyang University Erica Campus, Gyeonggi-do, KR;

Inventors:

Yong-Hee Kim, Seoul, KR;

Tae-Hwan Kim, Seoul, KR;

Chul-Su Yang, Gyeonggi-do, KR;

Yoonsung Song, Gyeonggi-do, KR;

Jee-Young Chung, Seoul, KR;

Sungsin Jo, Gyeonggi-do, KR;

So Mi Kim, Seoul, KR;

Qurrat Ui Ain, Seoul, KR;

Ye-Ram Kim, Daejeon, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); A61K 47/62 (2017.01); C12N 15/113 (2010.01); A61K 31/7088 (2006.01); A61P 37/06 (2006.01); A61P 19/02 (2006.01); A61K 47/64 (2017.01);
U.S. Cl.
CPC ...
A61K 47/62 (2017.08); A61K 31/7088 (2013.01); A61K 47/6455 (2017.08); A61P 19/02 (2018.01); A61P 37/06 (2018.01); C12N 15/1137 (2013.01); C12Y 304/24086 (2013.01); C12N 2310/122 (2013.01); C12N 2310/14 (2013.01); C12N 2310/351 (2013.01); C12N 2310/3517 (2013.01); C12N 2310/531 (2013.01); C12N 2320/32 (2013.01);
Abstract

Disclosed is a gene/carrier complex for preventing or treating inflammatory diseases, including tumor necrosis factor-α converting enzyme (TNF-α converting enzyme, TACE) shRNA and a nonviral gene carrier, wherein the nonviral gene carrier includes an acetate of disulfide-linked poly(oligo-arginine) or a TFA salt of poly(oligo-aspartic acid)poly(oligo-arginine).


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