The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Jul. 26, 2016
Applicant:
Cellectis, Paris, FR;
Inventor:
Mathilde Dusseaux, Maisons-Alfort, FR;
Assignee:
Cellectis, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); C07K 14/705 (2006.01); C07K 16/28 (2006.01); A61K 39/395 (2006.01); C12N 5/0783 (2010.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0011 (2013.01); A61K 39/39558 (2013.01); A61P 35/00 (2018.01); C07K 14/70596 (2013.01); C07K 16/2803 (2013.01); C07K 16/2896 (2013.01); C12N 5/0636 (2013.01); A61K 2039/5158 (2013.01); A61K 2039/55522 (2013.01); C07K 2317/622 (2013.01); C07K 2319/03 (2013.01); C07K 2319/33 (2013.01);
Abstract
Methods of developing genetically engineered immune cells for immunotherapy, which can be endowed with Chimeric Antigen Receptors targeting an antigen marker that is common to both the pathological cells and said CD38 immune by the fact that the genes encoding said markers are inactivated in said immune cells by a rare cutting endonuclease such as TALEN, Cas9 or argonaute.