The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Dec. 23, 2015
Guangzhou Ribobio Co., Ltd., Guangzhou, CN;
Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, CN;
Bill Biliang Zhang, Guangzhou, CN;
Micky Daniel Tortorella, Guangzhou, CN;
Zhe Wang, Guangzhou, CN;
Xiuqun Yang, Guangzhou, CN;
Qiuyun Wang, Guangzhou, CN;
GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES, Guangzhou, CN;
GUANGZHOU RIBOBIO CO., LTD., Guangzhou, CN;
Abstract
Provided are siRNAs or chemically-modified siRNAs targeted against ADAMTS-5 or ADAM17 for inhibiting the expression of ADAMTS-5 or ADAM17. Use of the siRNAs for treating an ADAMTS-5 or ADAM17 associated disease, such as arthritis and other inflammation-related diseases, by injecting the siRNAs or preparations comprising the siRNAs into an articular cavity of the patient, are also provided.