logo

For the Inventor, By the Inventor

The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10709717 B1

PDFFull Text
Date of Patent:
Jul. 14, 2020

Filed:

Oct. 13, 2015

Polymer composed of repeat units having a biologically active molecule attached thereto via a ph-sensitive bond

Applicant:

Spirea Limited, Harrogate, GB;

Inventors:

Myriam Marie Ouberai, Cambridge, GB;

Mark Welland, Cambridge, GB;

Assignee:

SPIREA LIMITED, Harrogate, GB;

Attorney:

Christensen O'Connor Johnson Kindness PLLC

Primary Examiner:

Alma Pipic

Int. Cl.
CPC ...
A61K 31/13 (2006.01); A61K 31/133 (2006.01); A61K 31/138 (2006.01); A61K 31/4409 (2006.01); A61K 31/496 (2006.01); A61K 31/573 (2006.01); A61K 9/51 (2006.01); C08G 63/672 (2006.01); A61K 45/06 (2006.01); C08G 63/685 (2006.01); C08G 63/16 (2006.01); A61K 47/59 (2017.01); C08G 63/688 (2006.01); A61K 9/50 (2006.01); C08G 63/91 (2006.01); C12P 7/62 (2006.01);
U.S. Cl.
CPC ...
A61K 31/573 (2013.01); A61K 9/5031 (2013.01); A61K 9/5146 (2013.01); A61K 31/13 (2013.01); A61K 31/133 (2013.01); A61K 31/138 (2013.01); A61K 31/4409 (2013.01); A61K 31/496 (2013.01); A61K 45/06 (2013.01); A61K 47/593 (2017.08); C08G 63/16 (2013.01); C08G 63/672 (2013.01); C08G 63/6856 (2013.01); C08G 63/6886 (2013.01); C08G 63/916 (2013.01); C12P 7/62 (2013.01); C12Y 301/01003 (2013.01); Y02A 50/483 (2018.01);
Abstract

There is provided a polymer comprising: (i) a repeat unit derived from a compound of formula (I) (Formula (I)) wherein, Rand Rare each independently selected from OH, OR', SH, SR′, NH, NHR′ and NR′; R′ is Chydrocarbyl; each n is independently 0 or an integer between 1 and 6; each m is independently 0 or an integer between 1 and 4, and preferably at least one m is 1; and q is an integer between 1 and 8; and; (ii) a biologically active molecule, wherein said biologically active molecule is covalently bonded to said repeat unit; as well as methods for preparing such polymers, particles comprising said polymers and uses of said polymers and particles including use in the treatment of disease.

Find Patent Forward Citations

Loading…