The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Jul. 02, 2015
Applicant:
Inflectis Bioscience, Nantes, FR;
Inventor:
Philippe Guedat, Montenois, FR;
Assignee:
INFLECTIS BIOSCIENCE, Nantes, FR;
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/155 (2006.01); A61K 31/44 (2006.01); A61K 31/53 (2006.01);
U.S. Cl.
CPC ...
A61K 31/155 (2013.01); A61K 31/44 (2013.01); A61K 31/53 (2013.01);
Abstract
The present invention relates to novel uses of a compound of formula (I), or a tautomer and/or a pharmaceutically acceptable salt thereof, in treating a disorder associated with the PPP1R15A pathway and associated with protein misfolding stress and in particular with accumulation of misfolded proteins selected in the group of tauopathies, synucleinopathies, polyglutamine and polyalanine diseases, leukodystrophies, cystic fibrosis, multiple sclerosis, lysosomal storage disorders, amyloidosis diseases, inflammation, metabolic disorders, cardio-vascular disorders, osteoporosis, nervous system trauma, ischemia.