The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 14, 2020

Filed:

Sep. 08, 2017
Applicant:

Geneheal Biotechnology Co., Ltd., Guangdong, CN;

Inventors:

Wuguang Pan, Guangdong, CN;

Wei Zhu, Guangdong, CN;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/132 (2006.01); C07C 209/00 (2006.01); C07D 501/57 (2006.01); A61P 3/00 (2006.01); A61K 31/663 (2006.01); A61K 38/17 (2006.01); A61K 31/16 (2006.01); A61K 38/06 (2006.01); A61K 31/407 (2006.01); A61P 25/14 (2006.01); A61K 31/198 (2006.01); C07F 9/90 (2006.01); C07C 221/00 (2006.01); A61P 43/00 (2006.01); C07D 405/14 (2006.01); A61K 31/427 (2006.01); A61P 25/08 (2006.01); C07C 249/00 (2006.01); A61K 8/41 (2006.01); A61K 31/00 (2006.01); A61K 31/341 (2006.01);
U.S. Cl.
CPC ...
A61K 31/132 (2013.01); A61K 8/41 (2013.01); A61K 31/00 (2013.01); A61K 31/16 (2013.01); A61K 31/198 (2013.01); A61K 31/341 (2013.01); A61K 31/407 (2013.01); A61K 31/427 (2013.01); A61K 31/663 (2013.01); A61K 38/06 (2013.01); A61K 38/17 (2013.01); A61P 3/00 (2018.01); A61P 25/08 (2018.01); A61P 25/14 (2018.01); A61P 43/00 (2018.01); C07C 209/00 (2013.01); C07C 221/00 (2013.01); C07C 249/00 (2013.01); C07D 405/14 (2013.01); C07D 501/57 (2013.01); C07F 9/90 (2013.01);
Abstract

Provided are applications of spermine and derivatives thereof. On the basis of existing protein structure data and small molecule structure data, calculations and analysis are performed using software to screen and obtain compounds capable of effectively interfering with PAICS activity, reducing SAICAR synthesis, and ultimately reducing SAICAR accumulation, in order to achieve the goal of treating or reducing ADSL deficiency. A better effect in the treatment or improvement of ADSL deficiency is expected from the joint use of at least two of the described compounds.


Find Patent Forward Citations

Pan, Wuguang. (2020). Applications of spermine and derivatives thereof (U.S. Patent No. 10709676). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10709676

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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