The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Jan. 03, 2019
Applicant:
Yale University, New Haven, CT (US);
Inventors:
Assignee:
Yale University, New Haven, CT (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/127 (2006.01); A61K 47/58 (2017.01); A61K 47/69 (2017.01); B82Y 5/00 (2011.01); A61K 47/24 (2006.01); A61K 47/40 (2006.01); A61K 38/18 (2006.01); A61K 38/20 (2006.01); A61K 31/343 (2006.01); A61K 47/68 (2017.01); A61K 9/00 (2006.01); A61K 9/51 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
A61K 9/127 (2013.01); A61K 9/0019 (2013.01); A61K 9/1271 (2013.01); A61K 9/1273 (2013.01); A61K 9/1277 (2013.01); A61K 9/5153 (2013.01); A61K 31/343 (2013.01); A61K 38/1841 (2013.01); A61K 38/2013 (2013.01); A61K 47/24 (2013.01); A61K 47/40 (2013.01); A61K 47/58 (2017.08); A61K 47/6849 (2017.08); A61K 47/6937 (2017.08); A61K 47/6951 (2017.08); B82Y 5/00 (2013.01); C07K 16/2812 (2013.01);
Abstract
Compositions and methods for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder are described herein. The compositions contain a nanolipogel for sustained delivery of an effective amount of one or more active agents of choice, preferably a drug for treating or ameliorating the symptoms of inflammatory or autoimmune disease or disorder. The nanolipogel includes a lipid bilayer surrounding a hydrogel core, which may optionally include a host molecule, for example, an absorbent such as a cyclodextrin or ion-exchange resin. In preferred embodiments at least one of active agents is an immunosuppressant.