The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 14, 2020
Filed:
Jan. 29, 2020
Applicants:
King Abdulaziz University, Jeddah, SA;
Virginia Commonwealth University, Richmond, VA (US);
Inventors:
Tarek A. Ahmed, Jeddah, SA;
Alaa O. Bawazir, Jeddah, SA;
Abdelsattar M. Omar, Jeddah, SA;
Martin K. Safo, Richmond, VA (US);
Assignees:
King Abdulaziz University, Jeddah, SA;
Virginia Commonwealth University, Richmond, VA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/00 (2006.01); A61K 47/40 (2006.01); A61K 47/32 (2006.01); A61K 9/107 (2006.01); A61K 47/24 (2006.01); A61K 31/351 (2006.01); A61K 9/14 (2006.01); A61P 1/16 (2006.01);
U.S. Cl.
CPC ...
A61K 9/006 (2013.01); A61K 9/1075 (2013.01); A61K 9/146 (2013.01); A61K 31/351 (2013.01); A61K 47/24 (2013.01); A61K 47/32 (2013.01); A61K 47/40 (2013.01);
Abstract
Mucoadhesive buccal films comprising a statin-hydroxypropyl-beta-cyclodextrin inclusion complex and a statin-loaded mixed micelle composition, wherein the ratio of the mixed micelle composition to the inclusion complex is from 2:0.5 to 2:1.5 are provided. Methods of improving permeation of a statin across mucosal tissue by administering the film to a subject are also provided.