The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Jun. 07, 2017
Applicant:

Biogen MA Inc., Cambridge, MA (US);

Inventors:

Meena Subramanyam, Stoneham, MA (US);

Lakshmi Amaravadi, Natick, MA (US);

Eric Wakshull, Princeton, MA (US);

Frances Lynn, Somerville, MA (US);

Michael Panzara, Winchester, MA (US);

Robin McDaid Barbour, Walnut Creek, CA (US);

Julie Elizabeth Taylor, San Francisco, CA (US);

Assignee:

BIOGEN MA INC., Cambridge, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/68 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
G01N 33/6854 (2013.01); C07K 16/2839 (2013.01); G01N 33/686 (2013.01); G01N 2333/70546 (2013.01); G01N 2800/065 (2013.01); G01N 2800/102 (2013.01); G01N 2800/285 (2013.01); G01N 2800/52 (2013.01);
Abstract

The invention relates to methods and products for the identification of a clinically significant immune response in subjects treated with a therapeutic protein. Aspects of the invention relate to methods and compositions for identifying a clinically significant immune response in patients treated with therapeutic amounts of a VLA4 binding antibody (e.g., natalizumab).


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