The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Jul. 25, 2014
Applicant:

Japanese Foundation for Cancer Research, Tokyo, JP;

Inventors:

Kengo Takeuchi, Tokyo, JP;

Yuki Togashi, Tokyo, JP;

Seiji Sakata, Tokyo, JP;

Satoko Baba, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); G01N 33/574 (2006.01); C12Q 1/6886 (2018.01); G01N 33/50 (2006.01); A61K 31/277 (2006.01); A61K 31/553 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5748 (2013.01); A61K 31/277 (2013.01); A61K 31/553 (2013.01); C12Q 1/6886 (2013.01); G01N 33/5017 (2013.01); G01N 33/5023 (2013.01); G01N 33/57419 (2013.01); G01N 33/57446 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01); G01N 2500/00 (2013.01);
Abstract

A polynucleotide, which is a novel causative gene for cancer, is elucidated, and, based on this finding, provided are a method for detecting the polynucleotide, or a polypeptide encoded by the polynucleotide; a kit and a primer set for the detection; a method for screening an inhibitor of the polypeptide; and a pharmaceutical composition for treating a cancer containing the inhibitor. In the detection method of the present invention, an NTRK3 fusion protein, or a fusion gene encoding the fusion protein, or an ETV6 fusion protein, or a fusion gene encoding the fusion protein, in a sample derived from the digestive system obtained from a subject, is detected.


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