The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Nov. 08, 2018
Applicant:

Hill's Pet Nutrition, Inc., Topeka, KS (US);

Inventors:

Samer Waleed Khedheyer Al-Murrani, Topeka, KS (US);

Xiangming Gao, Topeka, KS (US);

Assignee:

Hill's Pet Nutrition, Inc., Topeka, KS (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/04 (2006.01); C12Q 1/68 (2018.01); C12Q 1/6883 (2018.01); A23L 33/00 (2016.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6883 (2013.01); A23L 33/30 (2016.08); G01N 33/6893 (2013.01); A23V 2002/00 (2013.01); C12Q 2600/158 (2013.01); G01N 2800/046 (2013.01); G01N 2800/50 (2013.01);
Abstract

The present invention provides a method of diagnosing the existence or risk of hyperthyroidism in a feline comprising measuring the level of expression of one or more biomarkers selected from the group consisting of, e.g., IYD, TG, SLC5A5, NIS, TPO, TSHR, DUOX1, DUOX2 (ThOX), TGFB1, CSTD, DCN and SEPP1 and the expression products thereof, in a biological sample from the feline, wherein elevated expression of the one or more biomarkers in the sample relative to a control value for expression in a sample from a normal feline or feline population, or a baseline value from the feline, indicates the existence or risk of hyperthyroidism; a method of treating a feline so diagnosed; and compositions, reagents and kits for carrying out the specified methods.


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