The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Nov. 10, 2015
Applicants:
Capitalbio Corporation, Beijing, CN;
Tsinghua University, Beijing, CN;
Inventors:
Dong Wang, Beijing, CN;
Hui Wang, Beijing, CN;
Yan Zhang, Beijing, CN;
Guangxin Xiang, Beijing, CN;
Yimin Sun, Beijing, CN;
Wanli Xing, Beijing, CN;
Jing Cheng, Beijing, CN;
Assignees:
CAPITALBIO CORPORATION, Beijing, CN;
TSINGHUA UNIVERSITY, Beijing, CN;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/6876 (2018.01); C12Q 1/6827 (2018.01); C12Q 1/6858 (2018.01); C12Q 1/6883 (2018.01); C12Q 1/6853 (2018.01); C12Q 1/6869 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6876 (2013.01); C12Q 1/6827 (2013.01); C12Q 1/6853 (2013.01); C12Q 1/6858 (2013.01); C12Q 1/6869 (2013.01); C12Q 1/6883 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/16 (2013.01);
Abstract
Provided herein is a multi-sample and multi-locus method for analyzing a genetic locus. In particular, provided herein is a method for SNP detection and analysis based on high-throughput sequencing, comprising designing a probe, pre-amplification and biotin labeling, hybridization, ligation, barcode specific primer extension, sequencing and analyzing the SNP locus. A probe set is for the analysis is also provided.