The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Dec. 12, 2019
Bruce Mccord, Miami, FL (US);
Hussain Alghanim, Miami, FL (US);
Bruce McCord, Miami, FL (US);
Hussain Alghanim, Miami, FL (US);
THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES, Miami, FL (US);
Abstract
The invention pertains to analyzing the DNA methylation levels at specific genetic loci. The DNA methylation levels at the specific genetic loci can be used to detect the presence in a sample of a specific body fluid, for example, semen containing sperm, saliva, or blood. Particularly, the DNA methylation levels at the genetic loci corresponding to SEQ ID NOs: 1, 7, 13, and 19 are used to detect sperms, saliva or blood cells. The DNA methylation levels at the specific loci can be determined by high-resolution melt (HRM) analysis or sequencing of the amplicons produced using specific primers designed to amplify the specific loci. Kits containing the primers and reagents for carrying out the methods disclosed herein are also provided.