The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Aug. 09, 2018
Applicants:

Roche Diagnostics Operations, Inc., Indianapolis, IN (US);

Roche Diabetes Care, Inc., Indianapolis, IN (US);

Inventors:

Daniela Beck, Penzberg, DE;

Mara Boenitz-Dulat, Tutzing, DE;

Peter Kratzsch, Penzberg, DE;

Thomas Streidl, Seeshaupt, DE;

Carina Horn, Biblis, DE;

Assignee:

Roche Diabetes Care, Inc., Indianapolis, IN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/02 (2006.01); C12N 9/04 (2006.01); C12Q 1/32 (2006.01); C12P 7/18 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12P 7/18 (2013.01); C12Q 1/32 (2013.01); C12Y 101/0103 (2013.01);
Abstract

The present invention relates to a mutant 3-hydroxybutyrate dehydrogenase (3-HBDH) with improved performance relative to the wild-type 3-HBDH, a nucleic acid encoding the mutant 3-HBDH, a cell comprising the mutant 3-HBDH or the nucleic acid, a method of determining the amount or concentration of 3-hydroxybutyrate in a sample, and a device for determining the amount or concentration of 3-hydroxybutyrate in a sample.


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