The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Jul. 24, 2018
Applicant:
Antagonis Biotherapeutics Gmbh, Graz, AT;
Inventor:
Andreas Kungl, Graz, AT;
Assignee:
ANTAGONIS BIOTHERAPEUTICS GMBH, Graz, AT;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/54 (2006.01); C07K 14/52 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/5421 (2013.01); C07K 14/521 (2013.01); C07K 14/523 (2013.01); A61K 38/00 (2013.01); C07K 2319/31 (2013.01);
Abstract
The present invention relates to novel monomeric fusion proteins derived from human GAG binding proteins such as chemokines with increased glycosaminoglycan (GAG) binding affinity and knocked-out or reduced GPCR activity compared to wild type GAG binding proteins, which are highly selectively competitive and are of increased bioavailability, and to their use for prevention or treatment of pathological cell movement as in metastasis.