The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Apr. 10, 2018
Fujifilm Corporation, Tokyo, JP;
Koichi Minami, Ashigara-kami-gun, JP;
FUJIFILM Corporation, Tokyo, JP;
Abstract
Provided is a cyclic peptide, which is represented by Formula (I) or Formula (I') and has excellent antibody binding properties and improved chemical resistance, an affinity chromatography support, a labeled antibody, an antibody drug conjugate, and a pharmaceutical preparation.R-X-[X-X-X-X-X-X-X-X-X]-X-R  (I) In Formula (I), Xand Xeach independently represent an amino acid residue derived from an amino acid, other than L-cysteine and D-cysteine, having a thiol group on a side chain and are bonded to each other through a disulfide bond, or, one of Xand Xrepresents an amino acid residue derived from an amino acid, other than L-cysteine and D-cysteine, having a thiol group on a side chain and the other represents an amino acid residue derived from an amino acid having a haloacetyl group on a side chain, and Xand Xare bonded to each other through a thioether bond.R-X-[X-X-X-X-X-X-X-X-X]-X-R  (I′) In Formula (I′), one of Xand Xrepresents an amino acid residue derived from L-cysteine or D-cysteine and the other represents an amino acid residue derived from an amino acid having a haloacetyl group on a side chain, and Xand Xare bonded to each other through a thioether bond, or, one of Xand Xrepresents an amino acid residue derived from L-penicillamine or D-penicillamine and the other represents an amino acid residue derived from an amino acid having a haloacetyl group on a side chain, and Xand Xare bonded to each other through a thioether bond.