The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Apr. 19, 2016
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Atli Thorarensen, Stow, MA (US);

Matthew Frank Brown, Stonington, CT (US);

Agustin Casimiro-Garcia, Concord, MA (US);

Ye Che, Groton, CT (US);

Mark Edward Flanagan, Gales Ferry, CT (US);

Adam Matthew Gilbert, Guilford, CT (US);

Matthew Merrill Hayward, Old Lyme, CT (US);

Jean-Baptiste Telliez, Lexington, MA (US);

Rayomand Jal Unwalla, Bedford, MA (US);

John I. Trujillo, Ledyard, CT (US);

Sidney Xi Liang, Bethany, CT (US);

Assignee:

Pfizer Inc., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01);
Abstract

The present invention provides pharmaceutically active pyrrolo[2,3-d]pyrimidinyl, pyrrolo[2,3-b]pyrazinyl, and pyrrolo[2,3-b]pyridinyl acrylamides, epoxides, and analogues thereof. Such compounds are useful for inhibiting Janus Kinase (JAK). This invention also is directed to compositions comprising methods for making such compounds, and methods for treating and preventing conditions mediated by JAK.


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