The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Apr. 25, 2017
Applicant:

Sumitomo Dainippon Pharma Co., Ltd., Osaka-shi, Osaka, JP;

Inventors:

Shingo Tojo, Osaka, JP;

Yoshiaki Isobe, Osaka, JP;

Eiji Ideue, Osaka, JP;

Hiroaki Fujiwara, Tokyo, JP;

Daisuke Urabe, Osaka, JP;

Assignee:

SUMITOMO DAINIPPON PHARMA CO., LTD., Osaka-shi, Osaka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); A61K 31/5377 (2006.01); A61K 45/06 (2006.01); C07D 473/16 (2006.01); C07D 473/18 (2006.01); C07D 473/40 (2006.01); C07D 519/00 (2006.01); A61P 37/06 (2006.01); C07D 473/34 (2006.01); C07D 473/28 (2006.01);
U.S. Cl.
CPC ...
C07D 473/18 (2013.01); A61K 31/52 (2013.01); A61K 31/5377 (2013.01); A61K 45/06 (2013.01); A61P 37/06 (2018.01); C07D 473/16 (2013.01); C07D 473/28 (2013.01); C07D 473/34 (2013.01); C07D 473/40 (2013.01); C07D 519/00 (2013.01);
Abstract

The present invention relates to a substituted purine derivative of formula (1) wherein Ris alkoxy or the like, Ris alkyl or the like, Ring Qis aryl or the like, Wis alkylene or the like, Ring Qis aromatic carbocyclyl or the like, n is 1-4, Ris hydrogen atom or the like, Xis single bond or the like, Wis alkylene or the like, and Ris hydrogen atom or the like, or a pharmaceutically acceptable salt thereof, which has a potent inhibitory effect against TLR7, and thereby is useful for treating autoimmune disease.


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