The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Jul. 16, 2019
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Michael D. Altman, Needham, MA (US);
Brandon D. Cash, Stoughton, MA (US);
Wonsuk Chang, Princeton, NJ (US);
Jared N. Cumming, Winchester, MA (US);
Andrew M. Haidle, Somerville, MA (US);
Timothy J. Henderson, Natick, MA (US);
James P. Jewell, Newton, MA (US);
Matthew A. Larsen, Dedham, MA (US);
Rui Liang, New Brunswick, NJ (US);
Jongwon Lim, Lexington, MA (US);
Min Lu, Brookline, MA (US);
Ryan D. Otte, Natick, MA (US);
Tony Siu, Brookline, MA (US);
Benjamin Wesley Trotter, Medfield, MA (US);
Sriram Tyagarajan, Edison, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NY (US);
Abstract
Compounds of general formula (Ia), compounds of general formula (Ia'), compounds of general formula (Ib), compounds of general formula (Ib′), compounds of general formula (I), compounds of general formula (I′), and their pharmaceutically acceptable salts, wherein R, R, R, R, R, R, R, R, X, X, and Xare defined herein, that may be useful as inductors of type I interferon production, specifically as STING active agents, are provided. Also provided are processes for the synthesis and use of compounds of the disclosure.