The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Jun. 18, 2019
Applicant:

Scinopharm Taiwan, Ltd., Tainan, TW;

Inventors:

Wen-Wei Lin, Tainan, TW;

Tsung-Cheng Hu, Tainan, TW;

Yuan-Chang Huang, Tainan, TW;

Yung-Hung Chang, Tainan, TW;

Kuan-Hsun Wang, Tainan, TW;

Assignee:

ScinoPharm Taiwan, Ltd., Shan-Hua, Tainan, TW;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 237/32 (2006.01);
U.S. Cl.
CPC ...
C07D 237/32 (2013.01); C07B 2200/13 (2013.01);
Abstract

In certain aspects, the invention provides a novel crystalline form of olaparib (4-[(3-[(4-cyclopropylcarbonyl)piperazin-4-yl]carbonyl)-4-fluorophenyl]methyl(2H)phthalazin-1-one). In related aspects, the invention provides a processe for preparing the novel crystalline form of olaparib. The process includes forming a solution comprising crude olaparib and an organic solvent; adding the solution to an anti-solvent to form a slurry comprising a precipitate; isolating the precipitate; and drying the precipitate to obtain a crystalline form III of olaparib.


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