The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Feb. 28, 2019
Nihon Medi-physics Co., Ltd., Tokyo, JP;
National University Corporation Hokkaido University, Sapporo-shi, Hokkaido, JP;
Masato Kiriu, Tokyo, JP;
Soichi Nakamura, Tokyo, JP;
Yuji Kuge, Sapporo, JP;
Norifumi Abo, Sapporo, JP;
NIHON MEDI-PHYSICS CO., LTD., Koto-Ku, Tokyo, JP;
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY, Sapporo-Shi, Hokkaido, JP;
Abstract
A simple method for producing a clinically applicable radiopharmaceutical composition containing 1-(2,2-dihydroxymethyl-3-[F]fluoropropyl)-2-nitroimidazole ([F]DiFA) or a salt thereof as an active ingredient, is provided which includes a synthesis step of obtaining a crude product of [F]DiFA from a labeling precursor compound for [F]DiFA; and a purification step of purifying the crude product, in which the purification step includes purifying [F]DiFA using two or more different types of reverse phase solid phase extraction cartridges.