The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 07, 2020

Filed:

Apr. 27, 2018
Applicant:

Api Corporation, Tokyo, JP;

Inventors:

Jun Takehara, Fukuoka, JP;

Masato Murai, Fukuoka, JP;

Takashi Ohtani, Kanagawa, JP;

Tomoko Maeda, Kanagawa, JP;

Tsugihiko Hidaka, Fukuoka, JP;

Assignee:

API CORPORATION, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 211/60 (2006.01); C07C 309/66 (2006.01); C07C 233/47 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
C07D 211/60 (2013.01); C07C 233/47 (2013.01); C07C 309/66 (2013.01); C07D 498/08 (2013.01); Y02P 20/55 (2015.11);
Abstract

A method for producing (2S,5S)/(2R,5R)-5-hydroxypiperidine-2-carboxylic acid represented by the formula (10) below: the method including removing the protecting group from the hydroxyl group in a compound represented by formula (7) below: (wherein P represents a protecting group, Rrepresents an alkyl group containing 1 to 4 carbon atoms, and A represents an alkyl group containing 1 to 10 carbon atoms, an aryl group containing 6 to 12 carbon atoms, an alkyloxy group containing 1 to 4 carbon atoms, or an aralkyloxy group containing 7 to 20 carbon atoms)to synthesize a compound represented by formula (8) below: (wherein Rrepresents an alkyl group containing 1 to 4 carbon atoms, and A represents an alkyl group containing 1 to 10 carbon atoms, an aryl group containing 6 to 12 carbon atoms, an alkyloxy group containing 1 to 4 carbon atoms, or an aralkyloxy group containing 7 to 20 carbon atoms).


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