The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Jan. 06, 2017
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Board of Regents of the University of Texas System, Austin, TX (US);
John A. Katzenellenbogen, Urbana, IL (US);
Benita Katzenellenbogen, Urbana, IL (US);
Sung Hoon Kim, Champaign, IL (US);
Zeynep Madak-Erdogan, Champaign, IL (US);
Philip Shaul, Richardson, TX (US);
The Board of Trustees of the University of Illinois, Urbana, IL (US);
Board of Regents of the University of Texas System, Austin, TX (US);
Abstract
Provided are compounds of formulae provided herein. The compounds may include pathway-preferential estrogens (PaPEs) derivatives with tissue-selective activities. Also provided are pharmaceutical compositions comprising the compounds, as well as methods of treating a disease or condition including administering the compounds. The disease or condition may include postmenopausal symptoms, cardiovascular disease, stroke, vascular disease, bone disease, metabolic disease, arthritis, osteoporosis, obesity, vasomotor/hot flush, cognitive decline, cancer including breast cancer.