The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 07, 2020
Filed:
Oct. 04, 2017
Applicant:
Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL (US);
Inventor:
Jhumku D. Kohtz, Chicago, IL (US);
Assignee:
ANN AND ROBERT H. LURIE CHILDREN'S HOSPITAL OF CHICAGO, Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/44 (2006.01); A61K 38/00 (2006.01); A61P 25/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/443 (2013.01); A61K 38/005 (2013.01); A61P 25/00 (2018.01); C12Y 101/01 (2013.01);
Abstract
The present disclosure provides the use of Akr1b8, an agonist of Akr1b8, Akr1B10, or an agonist of Akr1B10 in methods and compositions for the treatment of neurological disorders and stress-induced conditions. Methods of increasing the levels of 5Thr3a on neuronal cells is also provided by contacting the neuronal cells with Akr1b8, an agonist of Akr1b8, Akr1B10, or an agonist of Akr1B10.