The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
Jun. 22, 2017
The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Board of Regents of the University of Nebraska, Lincoln, NE (US);
University of Rochester, Rochester, NY (US);
Arizona Board of Regents on Behalf of the University of Arizona, Tucson, AZ (US);
Universitat DE Barcelona, Barcelona, ES;
Fundacio Clinic, Barcelona, ES;
Hospital Clinic DE Barcelona, Barcelona, ES;
Julius-maximilians-university of Wurzburg, Wurzburg, DE;
British Columbia Cancer Agency Branch, Vancouver, CA;
Oslo University Hospital Hf, Oslo, NO;
Queen Mary and Westfield College, University of London, London, GB;
Louis M. Staudt, Bethesda, MD (US);
George Wright, Rockville, MD (US);
Sandeep Dave, Chapel Hill, NC (US);
Bruce Tan, Chicago, IL (US);
John I. Powell, Ijamsville, MD (US);
Wyndham Wilson, Washington, DC (US);
Elaine S. Jaffe, Great Falls, VA (US);
Wing C. Chan, Pasadena, CA (US);
Timothy C. Greiner, Council Bluffs, IA (US);
Dennis Weisenburger, Glendora, CA (US);
James Armitage, Omaha, NE (US);
Kai Fu, Omaha, NE (US);
Richard I. Fisher, Pittsford, NY (US);
Lisa M. Rimsza, Scottsdale, AZ (US);
Thomas Miller, Tucson, AZ (US);
Thomas Grogan, Tucson, AZ (US);
Elias Campo Guerri, Barcelona, ES;
Silvia M. Bea, Sabadell, ES;
Itziar Salaverria, Barcelona, ES;
Armando Lopez-Guillermo, Barcelona, ES;
Emilio Montserrat, Barcelona, ES;
Victor Moreno, Barcelona, ES;
Andreas Zettl, Wurzburg, DE;
German Ott, Bietigheim-Bissingen, DE;
Hans-Konrad Muller-Hermelink, Wurzburg, DE;
Andreas Rosenwald, Wurzburg, DE;
Julie Vose, Omaha, NE (US);
Randy Gascoyne, North Vancouver, CA;
Joseph Connors, Vancouver, CA;
Erlend B. Smeland, Oslo, NO;
Stein Kvaloy, Oslo, NO;
Harald Holte, Oslo, NO;
Jan Delabie, Toronto, CA;
T. Andrew Lister, London, GB;
The United States of America, as represented by the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Board of Regents of the University of Nebraska, Lincoln, NE (US);
University of Rochester, Rochester, NY (US);
Arizona Board of Regents on behalf of the University of Arizona, Tuscon, AZ (US);
Universitat de Barcelona, Barcelona, ES;
Fundacio Clinic, Barcelona, ES;
Hospital Clinic de Barcelona, Barcelona, ES;
Julius-Maximilians-University of Würzburg, Würzburg, DE;
British Columbia Cancer Agency Branch, Vancouver, CA;
Oslo University Hospital HF, Oslo, NO;
Queen Mary and Westfield College, University of London, London, GB;
Abstract
Gene expression data provides a basis for more accurate identification and diagnosis of lymphoproliferative disorders. In addition, gene expression data can be used to develop more accurate predictors of survival. The present invention discloses methods for identifying, diagnosing, and predicting survival in a lymphoma or lymphoproliferative disorder on the basis of gene expression patterns. The invention discloses a novel microarray, the Lymph Dx microarray, for obtaining gene expression data from a lymphoma sample. The invention also discloses a variety of methods for utilizing lymphoma gene expression data to determine the identity of a particular lymphoma and to predict survival in a subject diagnosed with a particular lymphoma. This information will be useful in developing the therapeutic approach to be used with a particular subject.