The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
Nov. 24, 2015
Applicants:
Christopher Kevil, Shreveport, LA (US);
Robert Mcvie, Shreveport, LA (US);
John Glawe, Benton, LA (US);
Inventors:
Christopher Kevil, Shreveport, LA (US);
Robert McVie, Shreveport, LA (US);
John Glawe, Benton, LA (US);
Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 33/564 (2006.01); C12Q 1/68 (2018.01); G01N 33/566 (2006.01); A61K 38/19 (2006.01); G01N 33/50 (2006.01); C12Q 1/6883 (2018.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
G01N 33/564 (2013.01); A61K 38/195 (2013.01); C12Q 1/6883 (2013.01); G01N 33/5091 (2013.01); G01N 33/566 (2013.01); A61K 49/0004 (2013.01); C12Q 2600/158 (2013.01); G01N 2333/7158 (2013.01); G01N 2800/042 (2013.01);
Abstract
CXCR4 and ROBO-1 are biomarkers associated with type 1 diabetes. Expression of CXCR4 and ROBO-1 in peripheral CD3 T cells is substantially higher in patients with autoimmune diabetes (type 1 diabetes) than in non-diabetic patients. Therapies are disclosed for reducing the progression of type 1 diabetes, and to reduce the risk of developing type 1 diabetes in patients who are at risk of developing type 1 diabetes.