The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
May. 20, 2019
University-industry Cooperation Group of Kyung Hee, Gyeonggi-do, KR;
Hong Kyu Lee, Yongsan-gu, KR;
Youngmi Kim, Gangnam-gu, KR;
UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY, Gyeonggi-do, KR;
Other;
Abstract
A biological detection method for dioxin compounds in serum and its diagnostic use in predicting metabolic syndrome and related conditions are disclosed. The method of detecting dioxin compounds include obtaining a serum sample by heat-inactivating total serum obtained from a subject, preparing a transformed cell line by introducing a recombinant vector comprising a gene construct in which at least one dioxin-responsive element is operably linked to a promoter and a reporter gene into a host cell, culturing the transformed cell line with the serum sample, detecting the activation of the reporter gene in the transformed cell line, and determining that the dioxin compound is included in the serum sample when the activation of the reporter gene is detected. The serum detected by the method can be used as a surrogate serum biomarker to correlate serum content with disease factors and to predict the occurrence of disease and determine treatability.