The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2020

Filed:

Apr. 27, 2012
Applicants:

Guido Franzoso, London, GB;

Laura Tornatore, London, GB;

Menotti Ruvo, San Nicola la Strada, IT;

Alberto Rocci, Turin, IT;

Antonio Palumbo, Turin, IT;

Inventors:

Guido Franzoso, London, GB;

Laura Tornatore, London, GB;

Menotti Ruvo, San Nicola la Strada, IT;

Alberto Rocci, Turin, IT;

Antonio Palumbo, Turin, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2018.01); C12Q 1/6886 (2018.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); C12Q 2600/118 (2013.01); C12Q 2600/158 (2013.01);
Abstract

A method of measuring Gadd45β expression comprising the step of measuring Gadd45β expression levels in a sample of cells, for example CD 138 expressing cells, obtained from a subject known to have or suspected of having a haematological malignancy. Expression levels may be used in diagnosis, for example of multiple myeloma, in providing a prognosis, for example in a patient having multiple myeloma or in guiding selection of an appropriate treatment agent, especially a treatment agent comprising Gadd45β and or MKK7 inhibitors. Also datasets comprising measured expression levels from multiple subjects.


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