The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2020

Filed:

Jul. 06, 2015
Applicant:

Universite Libre DE Bruxelles, Brussels, BE;

Inventors:

Laurence Van Melderen, Waterloo, BE;

Baptiste J. S. Dumont, Brussels, BE;

Thibaut Hallaert, Waterloo, BE;

Gilles Vanwalleghem, Rhode st Genèse, BE;

Philippe Goffin, Louvain-la-Neuve, BE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/65 (2006.01); C12P 21/02 (2006.01); C12N 15/70 (2006.01); C12N 15/10 (2006.01); C12N 15/66 (2006.01); C07K 14/245 (2006.01); C07K 14/435 (2006.01); C12N 15/81 (2006.01);
U.S. Cl.
CPC ...
C12P 21/02 (2013.01); C07K 14/245 (2013.01); C07K 14/43595 (2013.01); C12N 15/10 (2013.01); C12N 15/65 (2013.01); C12N 15/66 (2013.01); C12N 15/70 (2013.01); C12N 15/81 (2013.01); C07K 2319/50 (2013.01); C07K 2319/60 (2013.01); C07K 2319/92 (2013.01);
Abstract

A cassette sequence for the transformation of a host cell includes at least: a first nucleotide sequence encoding a peptide or protein of interest to be produced by the host cell. The first sequence is linked to a second nucleotide sequence providing resistance to a toxin or encoding an antitoxin peptide to the toxin. The nucleotide sequences are organized in such a way that production of the peptide encoded by the second nucleotide sequence(s) is translationally coupled to production of the peptide encoded by the first nucleotide sequence.


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