The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2020

Filed:

Aug. 28, 2019
Applicant:

President and Fellows of Harvard College, Cambridge, MA (US);

Inventors:

Alexander Watters, North Andover, MA (US);

Brendon Dusel, West Roxbury, MA (US);

Michael Super, Lexington, MA (US);

Mark Cartwright, West Newton, MA (US);

Donald E. Ingber, Boston, MA (US);

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); G01N 33/569 (2006.01); C07K 14/00 (2006.01); C07K 14/47 (2006.01); C07K 19/00 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); C07K 14/00 (2013.01); C07K 14/4726 (2013.01); C07K 19/00 (2013.01); G01N 33/569 (2013.01); A61K 38/00 (2013.01); C07K 2319/30 (2013.01); G01N 2333/78 (2013.01); G01N 2400/00 (2013.01);
Abstract

Described herein are engineered microbe-targeting molecules, microbe-targeting articles, kits comprising the same, and uses thereof. Such microbe-targeting molecules, microbe-targeting articles, or the kits comprising the same can not only bind or capture of a microbe or microbial matter thereof, but they also have improved capability (e.g., enhanced sensitivity or signal intensity) of detecting a microbe or microbial matter. Thus, the microbe-targeting molecules, microbe-targeting articles, and/or the kit described herein can be used in various applications, e.g., but not limited to assays for detection of a microbe or microbial matter, diagnostic and/or therapeutic agents for diagnosis and/or treatment of an infection caused by microbes in a subject or any environmental surface, and/or devices for removal of a microbe or microbial matter from a fluid.


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