The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
May. 01, 2019
Applicant:
Cognitive Research Enterprises, Inc., Morgantown, WV (US);
Inventors:
Thomas J. Nelson, Morgantown, WV (US);
Daniel L. Alkon, Chevy Chase, MD (US);
Assignee:
COGNITIVE RESEARCH ENTERPRISES, INC., Morgantown, WV (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 303/42 (2006.01); A61K 31/23 (2006.01); A61K 31/335 (2006.01); A61P 25/00 (2006.01); A61P 25/28 (2006.01); C07C 31/133 (2006.01); C07C 69/608 (2006.01); C07D 303/40 (2006.01); A61K 31/045 (2006.01); A61K 31/231 (2006.01); A61K 31/201 (2006.01); C07C 31/13 (2006.01); C07C 53/134 (2006.01); C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C07D 303/42 (2013.01); A61K 31/045 (2013.01); A61K 31/201 (2013.01); A61K 31/23 (2013.01); A61K 31/231 (2013.01); A61K 31/335 (2013.01); A61P 25/00 (2018.01); A61P 25/28 (2018.01); C07C 31/13 (2013.01); C07C 31/1333 (2013.01); C07C 53/134 (2013.01); C07C 69/608 (2013.01); C07D 303/40 (2013.01); C12N 9/12 (2013.01); C12Y 207/11013 (2013.01);
Abstract
The present invention relates to methods of activate an isoform of protein kinase C (PKC) for the treatment of neurological diseases including Alzheimer's disease and stroke using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids. The present invention also relates to methods of reducing neurodegeneration using cyclopropanated or epoxidized derivatives of mono- and polyunsaturated fatty acids.