The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 30, 2020
Filed:
Sep. 23, 2016
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventor:
Xu Wu, Lexington, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 249/12 (2006.01); C07D 249/14 (2006.01); C07D 285/125 (2006.01); C07D 277/74 (2006.01); C07D 271/113 (2006.01); C07D 213/82 (2006.01); C07D 401/12 (2006.01); C07D 401/14 (2006.01); A61P 35/00 (2006.01); G01N 33/68 (2006.01); G01N 33/50 (2006.01); C12Q 1/25 (2006.01);
U.S. Cl.
CPC ...
C07D 249/12 (2013.01); A61P 35/00 (2018.01); C07D 213/82 (2013.01); C07D 249/14 (2013.01); C07D 271/113 (2013.01); C07D 277/74 (2013.01); C07D 285/125 (2013.01); C07D 401/12 (2013.01); C07D 401/14 (2013.01); C12Q 1/25 (2013.01); G01N 33/5091 (2013.01); G01N 33/68 (2013.01);
Abstract
The present disclosure compounds, as well as their compositions and methods of use. The compounds inhibit the activity of the TEAD transcription factor, and are useful in the treatment of diseases related to the activity of TEAD transcription factor including, e.g., cancer and other diseases.