The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2020

Filed:

Mar. 11, 2016
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Jue Wang, Bridgewater, NJ (US);

Neil E. Jaffe, Newtown, PA (US);

Krina Patel, Easton, PA (US);

Assignee:

BRISTOL-MYERS SQUIBB COMPANY, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01D 15/38 (2006.01); C07K 1/22 (2006.01); C07K 16/00 (2006.01); B01D 15/20 (2006.01); B01D 15/42 (2006.01); G01N 30/50 (2006.01); C07K 16/06 (2006.01); B01D 15/18 (2006.01); G01N 30/88 (2006.01);
U.S. Cl.
CPC ...
B01D 15/20 (2013.01); B01D 15/1871 (2013.01); B01D 15/3809 (2013.01); B01D 15/424 (2013.01); C07K 1/22 (2013.01); C07K 16/00 (2013.01); C07K 16/065 (2013.01); G01N 30/50 (2013.01); C07K 2317/21 (2013.01); G01N 2030/8831 (2013.01);
Abstract

In certain embodiments, the invention provides a method of purifying a protein of interest from a mixture which comprises the protein of interest and one or more contaminants, said method comprising: a) subjecting the mixture to a first chromatography matrix, wherein the protein of interest binds to the first chromatography matrix; b) contacting the first chromatography matrix with a first wash solution which has a pH of at least 9.0, and does not comprise arginine or an arginine derivative; and c) eluting the protein of interest from the first chromatography matrix into an elution solution.


Find Patent Forward Citations

Wang, Jue. (2020). Use of alkaline washes during chromatography to remove impurities (U.S. Patent No. 10695693). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10695693

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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