The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2020

Filed:

Sep. 08, 2016
Applicant:

Clemson University, Clemson, SC (US);

Inventors:

Rachel McGuire, Little Mountain, SC (US);

Ryan Borem, Easley, SC (US);

Jeremy Mercuri, Piedmont, SC (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61L 27/36 (2006.01); A61L 27/52 (2006.01); A61L 27/50 (2006.01); A61F 2/08 (2006.01); A61F 2/44 (2006.01); A61F 2/30 (2006.01);
U.S. Cl.
CPC ...
A61L 27/3633 (2013.01); A61F 2/08 (2013.01); A61F 2/442 (2013.01); A61L 27/3604 (2013.01); A61L 27/3654 (2013.01); A61L 27/3658 (2013.01); A61L 27/3662 (2013.01); A61L 27/3683 (2013.01); A61L 27/50 (2013.01); A61L 27/52 (2013.01); A61F 2002/30009 (2013.01); A61F 2002/30971 (2013.01); A61F 2002/4435 (2013.01); A61F 2002/4495 (2013.01); A61F 2310/00371 (2013.01); A61L 2430/06 (2013.01); A61L 2430/10 (2013.01); A61L 2430/38 (2013.01);
Abstract

Biocompatible biomimetic materials that exhibit desirable mechanical properties while also encouraging cell ingrowth and proliferation are described. The biomaterials include a multi-layer laminate of three or more decellularized aligned collagen tissues. The individual layers are aligned with one another in an angle-ply arrangement, with the collagen of each layer aligned at an angle to the collagen of the adjacent layer. The biomaterials are useful as collagenous graft materials such as a patch for a hernia in an annulus fibrosus or grafting materials for repair of tendons, ligaments, cartilage and other musculoskeletal tissues.


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