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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10695365 B1

PDFFull Text
Date of Patent:
Jun. 30, 2020

Filed:

Jan. 23, 2018

Microporous zirconium silicate for the treatment of hyperkalemia

Applicant:

Zs Pharma, Inc., Coppell, TX (US);

Inventors:

Donald Jeffrey Keyser, Southlake, TX (US);

Alvaro F. Guillem, Lantana, TX (US);

Assignee:

ZS PHARMA, INC., Coppell, TX (US);

Attorneys:

Culhane Meadows PLLC

Jeff B. Vockrodt

Primary Examiner:

Kortney L Klinkel

Int. Cl.
CPC ...
A61K 33/24 (2019.01); A61K 33/00 (2006.01); A61K 9/14 (2006.01); C07F 7/02 (2006.01); C01B 39/00 (2006.01); C01B 33/20 (2006.01); A61K 9/10 (2006.01); A61K 45/06 (2006.01); B01J 39/02 (2006.01); B01J 19/00 (2006.01); B01J 39/14 (2006.01); B01J 19/18 (2006.01);
U.S. Cl.
CPC ...
A61K 33/24 (2013.01); A61K 9/10 (2013.01); A61K 9/14 (2013.01); A61K 9/143 (2013.01); A61K 33/00 (2013.01); A61K 45/06 (2013.01); B01J 19/006 (2013.01); B01J 19/0013 (2013.01); B01J 19/18 (2013.01); B01J 39/02 (2013.01); B01J 39/14 (2013.01); C01B 33/20 (2013.01); C01B 39/00 (2013.01); C07F 7/025 (2013.01); A61K 2300/00 (2013.01); B01J 2219/00063 (2013.01); B01J 2219/00094 (2013.01); B01J 2219/00768 (2013.01);
Abstract

The present invention relates to novel microporous zirconium silicate compositions that are formulated to remove toxins, e.g. potassium ions, from the gastrointestinal tract at an elevated rate without causing undesirable side effects. The preferred formulations are designed avoid increase in pH of urine in patients and/or avoid potential entry of particles into the bloodstream of the patient. Also disclosed is a method for preparing high purity crystals of ZS-9 exhibiting an enhanced level of potassium exchange capacity. These compositions are particularly useful in the therapeutic treatment of hyperkalemia.

Find Patent Forward Citations

Keyser, Donald. (2020). Microporous zirconium silicate for the treatment of hyperkalemia (U.S. Patent No. 10695365). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10695365

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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