The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 30, 2020

Filed:

Feb. 15, 2018
Applicants:

Washington University, Saint Louis, MO (US);

Oriental Yeast Co., Ltd., Tokyo, JP;

Inventors:

Jun Yoshino, Creve Coeur, MO (US);

Hisataka Yasuda, Shiga, JP;

Hideo Arai, Tokyo, JP;

Tetsuro Enomoto, Tokyo, JP;

Assignee:

Washington University, Saint Louis, MO (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/706 (2006.01); A61P 3/04 (2006.01); A61K 9/00 (2006.01); A61K 31/185 (2006.01); A61K 38/06 (2006.01); A61K 31/205 (2006.01); A61K 31/197 (2006.01); A61K 31/122 (2006.01); A61K 31/7012 (2006.01); A61K 31/7004 (2006.01); A61K 36/81 (2006.01); A61K 36/9068 (2006.01); A61K 36/185 (2006.01); A61K 36/77 (2006.01); A61K 36/38 (2006.01); A61K 31/198 (2006.01); A61K 31/165 (2006.01); A61K 31/702 (2006.01); A23L 33/13 (2016.01); A23K 20/153 (2016.01); A61P 3/10 (2006.01); A61K 45/06 (2006.01); A23L 33/20 (2016.01); A61K 8/67 (2006.01);
U.S. Cl.
CPC ...
A61K 31/706 (2013.01); A23K 20/153 (2016.05); A23L 33/13 (2016.08); A23L 33/20 (2016.08); A61K 9/0056 (2013.01); A61K 9/0095 (2013.01); A61K 31/122 (2013.01); A61K 31/165 (2013.01); A61K 31/185 (2013.01); A61K 31/197 (2013.01); A61K 31/198 (2013.01); A61K 31/205 (2013.01); A61K 31/702 (2013.01); A61K 31/7004 (2013.01); A61K 31/7012 (2013.01); A61K 36/185 (2013.01); A61K 36/38 (2013.01); A61K 36/77 (2013.01); A61K 36/81 (2013.01); A61K 36/9068 (2013.01); A61K 38/063 (2013.01); A61K 45/06 (2013.01); A61P 3/04 (2018.01); A61P 3/10 (2018.01); A23V 2002/00 (2013.01); A61K 8/675 (2013.01);
Abstract

The present disclosure provides for the administration of β-NMN, which increases the secretion of adiponectin. The present disclosure also provides an adiponectin secretion enhancer comprising β-nicotinamide mononucleotide, a pharmaceutically acceptable salt thereof or a solvate thereof, and a dietary supplement containing the aforementioned secretion enhancer, which can be ingested in order to increase the secretion of adiponectin. Also disclosed are methods of treating insulin resistance-related diseases such as of metabolic syndrome, diabetes, hyperlipidemia, fatty liver disease, hypertension, obesity, and arteriosclerosis.


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